Identification and Functional Analysis of Tomato BRI1 and BAK1 Receptor Kinase Phosphorylation Sites1[W][OPEN]
نویسندگان
چکیده
Department of Horticultural Science (V.S.B., X.W., S.K.M., S.K., G.A., S.D.C.) and Department of Molecular and Structural Biochemistry (R.K.B., M.B.G.), North Carolina State University, Raleigh, North Carolina 27695; Plant and Crop Sciences, University of Nottingham, Nottingham NG7 2RD, United Kingdom (E.L.W.); East Malling Research, East Malling, Kent ME19 6BJ, United Kingdom (G.J.B.); and United States Department of Agriculture/Agricultural Research Service, University of Illinois, Urbana, Illinois 61801 (S.C.H.)
منابع مشابه
Identification and functional analysis of tomato BRI1 and BAK1 receptor kinase phosphorylation sites.
Brassinosteroids (BRs) are plant hormones that are perceived at the cell surface by a membrane-bound receptor kinase, BRASSINOSTEROID INSENSITIVE1 (BRI1). BRI1 interacts with BRI1-ASSOCIATED RECEPTOR KINASE1 (BAK1) to initiate a signal transduction pathway in which autophosphorylation and transphosphorylation of BRI1 and BAK1, as well as phosphorylation of multiple downstream substrates, play c...
متن کاملIdentification and functional analysis of in vivo phosphorylation sites of the Arabidopsis BRASSINOSTEROID-INSENSITIVE1 receptor kinase.
Brassinosteroids (BRs) regulate multiple aspects of plant growth and development and require an active BRASSINOSTEROID-INSENSITIVE1 (BRI1) and BRI1-ASSOCIATED RECEPTOR KINASE1 (BAK1) for hormone perception and signal transduction. Many animal receptor kinases exhibit ligand-dependent oligomerization followed by autophosphorylation and activation of the intracellular kinase domain. To determine ...
متن کاملTyrosine-610 in the Receptor Kinase BAK1 Does Not Play a Major Role in Brassinosteroid Signaling or Innate Immunity
The plasma membrane-localized BRI1-ASSOCIATED KINASE1 (BAK1) functions as a co-receptor with several receptor kinases including the brassinosteroid (BR) receptor BRASSINOSTEROID-INSENSITIVE 1 (BRI1), which is involved in growth, and the receptors for bacterial flagellin and EF-Tu, FLAGELLIN-SENSING 2 (FLS2) and EF-TU RECEPTOR (EFR), respectively, which are involved in immunity. BAK1 is a dual s...
متن کاملFunctional importance of BAK1 tyrosine phosphorylation in vivo.
The plant receptor kinase BRI1-ASSOCIATED RECEPTOR KINASE 1 (BAK1) is known as a partner of several ligand-binding leucine-rich repeat receptor kinases, including BRASSINOSTEROID INSENSITIVE 1 (BRI1) and the flagellin receptor FLS2. Autophosphorylation of receptor kinases is recognized to be an important process in receptor kinase signaling, and at least with the recombinant protein, BAK1 was s...
متن کاملBRI1/BAK1, a Receptor Kinase Pair Mediating Brassinosteroid Signaling
The Arabidopsis BAK1 (BRI1 Associated receptor Kinase 1) was identified by a yeast two-hybrid screen as a specific interactor for BRI1, a critical component of a membrane brassinosteroid (BR) receptor. In yeast, BAK1/BRI1 interaction activates their kinase activities through transphosphorylation. BAK1 and BRI1 share similar gene expression and subcellular localization patterns and physically as...
متن کامل